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Gut-Heart Axis: CVD and Gut Microbiota

Updated: Feb 19

Welcome to this week’s article of Bites of Wisdom! With February being Heart Health Month, I think it is the perfect time to answer questions crucial for cardiovascular well-being!!

If you guessed we're exploring the vital Gut-Heart connection today, you're spot on – and about to gain some valuable insights.

Let's dive in!

What is the Gut-Heart Axis?

The Gut-Heart Axis refers to the intricate relationship between the gut microbiota, intestinal barrier, and systemic inflammation, which significantly influences cardiovascular health. The gut microbiota, a diverse community of microorganisms in the gut, plays a pivotal role in various physiological processes. Imbalances in the gut microbiota, known as dysbiosis, have been linked to inflammatory conditions and cardiovascular disease.

How does the gut microbiome affect cardiovascular disease (CVD)?

The gut microbiome influences cardiovascular health through the production and metabolism of hormones and neurotransmitters, modulation of inflammation, and effects on cholesterol metabolism. Dysbiosis in the gut microbiota has been connected to the development and progression of cardiovascular diseases such as coronary heart disease, stroke, hypertension, and atherosclerosis.

How can functional nutrition address gut and heart health?

Functional nutrition takes a comprehensive and integrative approach to addressing cardiovascular disease, focusing on factors such as diet, lifestyle, genetics, and gut health. By assessing the balance of the gut microbiota, identifying dysbiosis, and considering factors such as gut permeability and inflammation, functional nutrition seeks to personalize interventions to optimize gut function and positively impact cardiovascular outcomes.

I hope you enjoyed this article!

Just a friendly reminder that while I'm passionate about sharing valuable research and information through my blog, our personalized 1:1 services extend far beyond simple FAQs! If you're seeking a tailored care plan, feel free to reach out to our dedicated team to schedule a consultation. We're here to help you achieve a healthy heart and gut more effectively.

Disclaimer: The information provided is as a community service to learn more about general health topics and does not replace medical advice. Always consult with your doctor before making changes to your diet, exercise, and supplement protocols. We never suggest stopping prescription medications. Our content is designed to be the latest, evidence-based knowledge pulling from reliable sources such as current research and the Institute of Functional Medicine. All statements have not been evaluated by the FDA nor are they intended to prevent, diagnose, treat or cure any disease. If you have any questions, please contact us at As with all educational materials designed for large groups, utilize what interests you and do your own research, discard what doesn’t serve you.


Cloyd, J. (2023, December 5). The impact of gut health on cardiovascular disease: Insights from functional medicine. Rupa Health.

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